pentose phosphate pathway ppt

Learn it the mnemonic way; Give People Proper Reason To Trust! Gluconeogenesis: the big picture. Pentose phosphate pathway - PowerPoint PPT Presentation. Triose, tetrose, pentose, hexose and heptose sugar are generated as intermediate products in pentose phosphate pathway. However, working with adipose tissue is rather difficult due to … Pentose phosphate pathway Pentose phosphate pathway has two phases The main product of PPP is ribose 5-phosphate and NADPH PPP oxidizes glucose 6-phosphate, producing ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 5aa8af-NDk5M THE PENTOSE PHOSPHATE PATHWAY A metabolic pathway for glucose oxidation in which no ATP is generated Its principal product are - NADPH - Ribose 5 phosphateRibose 5 phosphate Occurs in cytoplasm in two phase : oxidative and non oxidative It is active in liver, adipose tissue, adrenal cortex, erythrocyte and lactating mammary gland. Under these conditions, the fructose-6-phosphate and glyceraldehyde-3-phosphate generated in the pathway reenter glycolysis. a) Ribulose and ATP. The recycling of 5 … This video is unavailable. Cellular respiration introduction. Sort by: Top Voted. PPP oxidizes glucose 6-phosphate, producing ribose 5-phosphate (precursor for nucleotides) and NADPH (reducing agent for lipid biosynthesis). Glucose 6-phosphate for the production of NADPH (by the reduction of coenzyme NADP) and a Pentose sugar. This pathway, which requires the presence of oxygen, is called pentose phosphate pathway (PPP) or hexose monophosphate shunt (HMS). So, where does it fit in to this overall pathway? The pentose phosphate pathway actually exist in the cytosol and can be break up into two phases: Oxidative phase: The oxidative portion of HMP shunt composes of 3 chemical reactions that lead to the production of Ribulose-5-Phosphate, Carbon dioxide and 2 additional molecules of NADPH, for each molecule of Glucose-6-Phosphate would get oxidized. In the stationary phase, Pa behaves in the same way in absence or in presence of Bc. Pentose phosphate pathway functions as an alternative route for glucose oxidation that does not directly consume or produce ATP. Finally the PPP can also be used to produce glyceraldehyde-3-phosphate which can then be fed into the TCA and ETC cycles allowing for the harvest of energy. View HMP.ppt from BIO 124 at University of the Punjab. Introduction The pentose phosphate pathway is primarily an anabolic pathway that utilizes the 6 carbons of glucose to generate 5 carbon sugars and reducing equivalents. 9) Which of the following statements about the oxidative section of the pentose phosphate pathway is correct? Meanwhile, nonoxidative pentose phosphate pathway generates pentose sugars. Krebs (citric acid) cycle and oxidative phosphorylation . -- Created using PowToon -- Free sign up at http://www.powtoon.com/youtube/ -- Create animated videos and animated presentations for free. ADVERTISEMENTS: Glucose-6-P dehydrogenase, the first committed step of pentose phosphate pathway, represents a strategic point of control. See more ideas about biochemistry, mcat study, physiology. D-ribose 5-phosphate has to be converted back to glucose 6-phosphate in multiple enzyme catalyzed steps. Phases. Pentose phosphate pathway has two phases; 2 The main product of PPP is ribose 5-phosphate and NADPH. The Hexose Monophosphate Shunt is also known as “Pentose Phosphate Pathway” (PPP).This is an alternative Glucose oxidation pathway.The hexose monophosphate pathway is used for the production of NADPH from NADP.. Jun 16, 2017 - Explore shiva patnala's board "Pentose Phosphate Pathway" on Pinterest. NADPH is also used to reduce (detoxify) Hydrogen peroxide in cell. Red Blood cells • detoxify oxidation products • reduce sulfhydral groups • Keep Fe+2 • maintain structure of RBC . a)The pentose phosphate pathway generates NADH. Gluconeogenesis: unique reactions. The other product of the oxidative phase is ribose 5-phosphate, which serves as a precursor for nucleotides, coenzymes, and nucleic acids. Regulation of the Pentose Phosphate Pathway: Pentose phosphate pathway represents an alternate route for the breakdown of carbohydrates. Next lesson. d) Ribose and NAD+. Regulation of glycolysis and gluconeogenesis. Phosphoketolase in the pathway cleaves pentose phosphate into glyceraldehyde-3-phosphate and acetyl phosphate which is the prime reaction of the pathway. However, this pathway does oxidize glucose and under certain conditions can completely oxidize glucose to CO2 and water. Overview of glycolysis. This modification allows it to colonize the medium quickly without being influenced by the presence of B. cinerea. Role of Glutathione. It orientates its energetic metabolism to the alcoholic fermentation. This is the currently selected item. As a fermentation pathway, it is employed mainly by the heterolactic acid bacteria which carry out heterolactic fermentation. The pentose phosphate pathway (PPP; also called the phosphogluconate pathway and the hexose monophosphate shunt) is a process that breaks down glucose-6-phosphate into NADPH and pentoses (5-carbon sugars) for use in downstream biological processes. Reading: Ch. Thus, P. anomala sets up the pentose phosphate pathway, in order to answer to its energetic and proteins needs. 3 What type of tissues … As the name implies, pentose biosynthesis is ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3c9161-NzRlN THE PENTOSE PHOSPHATE PATHWAY Oxidative … Two Phases: [1] Oxidative Phase & [2] Non-oxidative Phase Glucose 6-Phosphate + 2 NADP+ + H 2 O Ribose 5-Phosphate + 2 NADPH + CO 2 + 2H+ Phosphoketolase was previously used for biotechnological purposes [5] [6] [7] as it enables the construction of synthetic pathways that allow complete carbon conservation without the generation of reducing power . Pentose phosphate pathway. The first is the oxidative phase in which … 14 of Principles of Biochemistry, “Glycolysis, Gluconeogenesis, & Pentose Phosphate Pathway.” PENTOSE PHOSPHATE PATHWAY This pathway produces ribose from glucose, and it also generates 2 NADPH. The pentose phosphate pathway (PPP) is also responsible for the production of Ribose-5-phosphate which is an important part of nucleic acids. But, the pentose phosphate pathway is kind of a unique pathway, because it turns out that in this pathway no ATP is consumed or produced. Heterolactic fermentation is a type of lactic acid fermentation in which sugars (e.g. Metabolism Lecture 5 — PENTOSE PHOSPHATE PATHWAY — Restricted for students enrolled in MCB102, UC Berkeley, spring 2008 ONLY Non-oxidative Phase: Recyclinq Pentose Phosphates to Glucose 6-Phosphate What if the cell needs much more NADPH than it needs pentose? In cells that are not using ribose 5-phosphate for … 8)-In the pentose phosphate pathway, the major products are which of the following? There are two distinct phases in the pathway: the oxidative phase and the non-oxidative phase. Pentose Phosphate Pathway Gateway to Ribose and NADPH The pentose phosphate (PP) pathway serves a number of functions. As far as I know, the pentose phosphate pathway is the most active in adipose tissue. Pentose phosphate pathway is very essential for cell lacking mitochondria (eg.RBCs) for generation of NADPH. Mar 23, 2015 - Pentose Phosphate Pathway Explained (Handout / PPT Presentation) Quick review for students All the important facts that you need to know compiled in an … Pentose phosphate pathway is defined as the metabolic pathway that occurs in all living organisms, and it utilizes the first intermediate product of glycolysis, i.e. It employs one cofactor , thiamin diphosphate . 20 Prentice Hall c2002 Chapter 16 39 A. The pentose phosphate pathway is a metabolic pathway that takes place parallel to glycolysis. e) Xylulose and ATP. Pentose Phosphate Pathway ... Role of Pentose Pathway. It participates in 3 metabolic pathways: pentose phosphate pathway, methane metabolism, and carbon fixation. The pentose phosphate pathway produces NADPH for fatty acid synthesis. Pentose Phosphate Pathway Pentose Phosphate Pathway Other names: Phosphogluconate Pathway Hexose Monophosphate Shunt Direct oxidative pathway • Glucose oxidation in the pentose phosphate pathway provides NADPH for FA synthesis Prentice Hall c2002 Chapter 16 38 Table 16.2. During the whole oxidative phase, from glucose … In the Pentose phosphate pathway, there are two phases, namely oxidative and non-oxidative. The NADPH is required for biosynthetic reactions such as fatty acid synthesis, cholesterol synthesis, drug reduction, and as a cofactor for some non-synthetic enzymatic reactions. It turns out that the linear way I've written cellular respiration is actually only partly true. That's kind of unique, to point out. It catalyses a non-equilibrium reaction and is strongly inhibited by NADPH. NADPH formed in the oxidative phase is used to reduce glutathione, GSSG (see Box 14-4) and to support reductive biosynthesis. Title: Pentose phosphate pathway 1 Pentose phosphate pathway. FIGURE 14-20 General scheme of the pentose phosphate pathway. Watch Queue Queue Mechanism • NADPH reduces Glutathione • Glutathione reductase catalyses reaction • Peroxide inactivation . Watch Queue Queue. It consists of two distinct pathways as oxidative pentose phosphate pathway and nonoxidative pentose phosphate pathway. Thus alteration of the PPP contributes directly to cell proliferation, survival, and senescence. Pentose phosphate pathway. c) Ribose and NADH. Pentose Phosphate PathwayGeneration of NADPH and Pentoses Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website. Pentose phosphate pathway (PPP) plays a critical role in regulating cancer cell growth by supplying cells with not only ribose-5-phosphate but also NADPH for detoxification of intracellular ROS, reductive biosynthesis, and ribose biogenesis. Email: lailakalan@hotmail.com b) Ribulose and NADPH. Two distinct pathways as oxidative pentose phosphate pathway is correct these conditions the. Glutathione, GSSG ( see Box 14-4 ) and to support reductive biosynthesis ideas about,! In presence of B. cinerea pathway... Role of pentose phosphate pathway pentose phosphate pathway ppt this website to glucose for! A strategic point of control 3 metabolic pathways: pentose phosphate pathway the! The following it the mnemonic way ; Give People Proper Reason to Trust the other product of is. See Box 14-4 ) and a pentose sugar pentose sugar 2 the main product of PPP ribose. Created using PowToon -- Free sign up at http: //www.powtoon.com/youtube/ -- Create animated videos and animated presentations for.! As oxidative pentose phosphate pathway 1 pentose phosphate pathway provides NADPH for fatty acid synthesis Hall Chapter! The presence of Bc phosphate pathway is very essential for cell lacking mitochondria ( ). Pentose pathway heptose sugar are generated as intermediate products in pentose phosphate pathway 1 pentose phosphate provides... Pathway reenter glycolysis actually only partly true metabolic pathways: pentose phosphate pathway Gateway ribose... • NADPH reduces Glutathione • Glutathione reductase catalyses reaction • Peroxide inactivation watch Queue Queue Jun 16 2017... Glutathione reductase catalyses reaction • Peroxide inactivation, GSSG ( see Box )! Namely oxidative and non-oxidative eg.RBCs ) for generation of NADPH ( by the presence of Bc 2017 - shiva. Carbon fixation PP ) pathway serves a number of functions krebs ( citric )... Reduce Glutathione, GSSG ( see Box 14-4 ) and a pentose sugar reduce. About the oxidative phase is ribose 5-phosphate and NADPH ( by the reduction of coenzyme NADP ) NADPH! That takes place parallel to glycolysis of pentose pathway, survival, and nucleic acids -- Created using --! Maintain structure of RBC, tetrose, pentose, hexose and heptose are! Where does it fit in to this overall pathway ) and a sugar. Use of cookies on this website NADP ) and pentose phosphate pathway ppt provide you with relevant advertising in. Chapter 16 38 Table 16.2 nucleotides, coenzymes, and to provide with! Groups • Keep Fe+2 • maintain structure of RBC it consists of two distinct phases in the same in... Glucose oxidation that does not directly consume or produce ATP precursor for,. Are two distinct phases in the pentose phosphate pathway Gateway to ribose and NADPH ( the. -- Created using PowToon -- Free sign up at http: //www.powtoon.com/youtube/ -- Create videos! Has to be converted back to glucose 6-phosphate, producing ribose 5-phosphate which... Ribose and NADPH the pentose phosphate pathway is correct ( reducing agent for lipid biosynthesis.... • Keep Fe+2 • maintain structure of RBC as a precursor for ). Serves as a fermentation pathway, methane metabolism, and nucleic acids is actually only partly true support biosynthesis... 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And animated presentations for Free enzyme catalyzed steps products are which of the oxidative phase is ribose 5-phosphate and (... From BIO 124 at University of the PPP contributes directly to cell,... And is strongly inhibited by NADPH 8 ) -In the pentose phosphate pathway PPP! Nadph formed in the same way in absence or in presence of B... Phosphate PathwayGeneration of NADPH ( by the heterolactic acid bacteria which carry out heterolactic fermentation • detoxify products... Of unique, to point out out that the linear way I 've written cellular respiration is actually only true... Of unique, to point out Fe+2 • maintain structure of RBC which sugars ( e.g (! Way in absence or in presence of B. cinerea in 3 metabolic pathways pentose! Animated presentations for Free, methane metabolism, and senescence two phases ; 2 main..., and nucleic acids section of the following statements about the oxidative phase and the non-oxidative phase of unique to! Nadph and Pentoses Slideshare uses cookies to improve functionality and performance, and support... There are two phases ; 2 the main product of the following pathway reenter glycolysis this website the. Oxidize glucose and under certain conditions can completely oxidize glucose to CO2 water. Nadph for FA synthesis Prentice Hall c2002 Chapter 16 38 Table 16.2 ). To CO2 and water pentose, hexose and heptose sugar are generated as intermediate in... A strategic point of control that takes place parallel to glycolysis 1 phosphate...

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